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Promotes cell death. Mediates IFN-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9. [UniProt]
The stated application concentrations are suggested starting points. Titration of the IFI27 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 72-106 from human IFI27 was used as the immunogen for the IFI27 antibody.
Aliquot the IFI27 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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