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- Email: info@nsjbio.com
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Hydroxysteroid 17-beta Dehydrogenase 13 Antibody HSD17B13/13108 recognizes hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13), a lipid droplet-associated protein that is highly enriched in the liver. HSD17B13 belongs to the short-chain dehydrogenase/reductase protein family and is also known as SCDR9 and DHB13. Its association with hepatic lipid droplets has linked the protein to lipid storage, metabolic regulation, and hepatocellular physiology.
HSD17B13 has enzymatic activity toward lipid-related substrates and has attracted considerable attention for its relationship with metabolic liver disease. Expression of the protein is associated with hepatic lipid metabolism, while human genetic studies have identified loss-of-function HSD17B13 variants associated with reduced risk of progression to more severe chronic liver disease. These findings have connected HSD17B13 biology with steatotic liver disease, steatohepatitis, fibrosis, cirrhosis, and other processes involving progressive liver injury.
As a member of the short-chain dehydrogenase/reductase family, HSD17B13 belongs to a broader group of enzymes involved in oxidation-reduction reactions with diverse biological substrates. Its liver-enriched expression and lipid droplet localization distinguish HSD17B13 as an important target for investigating relationships among lipid metabolism, hepatocyte biology, and liver disease. The association of naturally occurring loss-of-function variants with protection from progressive liver injury has also generated interest in HSD17B13 as a potential therapeutic target.
Clone HSD17B13/13108 is a mouse monoclonal antibody generated using a portion of amino acids 1-200 of the human protein as the immunogen. This HSD17B13 Protein Antibody is Protein Microarray Validated using a HuProt array containing more than 19,000 full-length human proteins, providing proteome-scale evidence supporting target selectivity. NSJ Bioreagents offers clone HSD17B13/13108 for researchers investigating HSD17B13 expression, hepatic lipid metabolism, and liver biology. A Hydroxysteroid 17-beta Dehydrogenase 13 Antibody provides a clone-defined reagent for studying this lipid droplet-associated metabolic protein.
For an HSD17B13 antibody with additional western blot, flow cytometry, and multi-species validation, see our HSD17B13 Antibody / SCDR9 Antibody page.
Optimal dilution of the Hydroxysteroid 17-beta Dehydrogenase 13 Antibody HSD17B13/13108 should be determined by the researcher.
A portion of amino acids 1-200 of the human protein was used as the immunogen for the Hydroxysteroid 17-beta Dehydrogenase 13 Antibody HSD17B13/13108.
Aliquot the Hydroxysteroid 17-beta Dehydrogenase 13 Antibody HSD17B13/13108 and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
HSD17B13 antibody, SCDR9 antibody, DHB13 antibody, Hydroxysteroid 17-beta dehydrogenase 13 antibody, 17-beta-hydroxysteroid dehydrogenase type 13 antibody
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