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Home >> Antibodies >> Huntingtin interacting protein 2 Antibody / HIP2 / UBE2K

Huntingtin interacting protein 2 Antibody / HIP2 / UBE2K (RQ6693)

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  Catalog No Formulation Size Price (USD)  
Image RQ6693 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Flow cytometry testing of rat RH35 cells with Huntingtin interacting protein 2 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Huntingtin interacting protein 2 antibody.
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Flow cytometry testing of rat RH35 cells with Huntingtin interacting protein 2 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Huntingtin interacting protein 2 antibody.
Western blot testing of 1) monkey COS-7, 2) human HEK293, 3) rat brain, 4) rat testis, 5) mouse brain and 6) mouse testis tissue lysate with Huntingtin interacting protein 2 antibody. Predicted molecular weight ~22 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat, Monkey
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt P61086
Applications Western blot : 1-2ug/ml
Flow cytometry : 1-3ug/million cells
Direct ELISA : 0.1-0.5ug/ml
Limitations This Huntingtin interacting protein 2 antibody is available for research use only.
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Description

The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.

Application Notes

Optimal dilution of the Huntingtin interacting protein 2 antibody should be determined by the researcher.

Immunogen

Recombinant human protein (amino acids D33-E195) was used as the immunogen for the Huntingtin interacting protein 2 antibody.

Storage

After reconstitution, the Huntingtin interacting protein 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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