- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
HSV1 Antibody Mouse Monoclonal / Herpes Simplex Virus Type I [clone HSVI/2095] (V8331)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
V8331-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 100 ug | 559 | |
|
|
V8331-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 20 ug | 259 | |
|
|
V8331SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 |
| Availability | 1-3 business days |
| Species Reactivity | HSV1 (Herpes Simplex Virus 1) |
| Format | Purified |
| Host | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1, kappa |
| Clone Name | HSVI/2095 |
| Purity | Protein G affinity chromatography |
| Localization | Nuclear, cytoplasmic |
| Applications | Immunohistochemistry (FFPE) : 1-2ug/ml |
| Limitations | This HSV1 antibody is available for research use only. |
|
Review this product on BioCompare and get a $20 Amazon gift card
|
Related Products
|
HSV1 antibody mouse monoclonal (clone HSVI/2095) recognizes Herpes simplex virus type 1, an enveloped double stranded DNA virus belonging to the Alphaherpesvirinae subfamily of the Herpesviridae family. HSV1 antibody, also referred to as Herpes simplex virus 1 antibody and HSV-1 antibody in the literature, detects viral antigens expressed during active lytic infection and reactivation. This mouse monoclonal antibody provides defined, clone-specific detection of HSV-1 proteins in infected cells and tissues.
Herpes simplex virus type 1 primarily infects epithelial cells of the oral and facial mucosa before establishing lifelong latency in sensory neurons, particularly within the trigeminal ganglia. During productive infection, HSV-1 expresses immediate early, early, and late proteins that regulate viral gene transcription, DNA replication, capsid assembly, and virion release. Reactivation from latency results in renewed viral protein synthesis and anterograde transport to peripheral tissues, producing recurrent lesions. Monitoring HSV-1 antigen expression is therefore central to studies of viral replication dynamics and latency models.
The HSV-1 genome encodes numerous structural and regulatory proteins, including envelope glycoproteins such as gB, gC, gD, and gE, as well as transcriptional regulators that localize predominantly to the nucleus during replication. Depending on the stage of infection, viral proteins may exhibit nuclear, cytoplasmic, or membranous localization. Clone HSVI/2095 recognizes HSV-1 antigens and supports consistent monoclonal detection of viral protein expression in research applications.
HSV-1 infection is associated with orolabial lesions, keratitis, encephalitis, and increased morbidity in immunocompromised individuals. In experimental systems, HSV-1 serves as a widely used model for studying viral latency, neuronal tropism, immune evasion, and antiviral therapeutic development. Detection of HSV-1 proteins using a defined mouse monoclonal clone facilitates reproducible analysis across independent experiments.
HSV1 antibody Mouse Monoclonal (clone HSVI/2095) is suitable for research applications focused on viral detection, host-pathogen interactions, and molecular characterization of Herpes simplex virus type 1 biology.
Optimal dilution of the HSV1 antibody should be determined by the researcher.
Baculovirus-expressed HSV DNA polymerase (POL) and POL/UL42 complex was used as the immunogen for this HSV1 antibody.
Store the HSV1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Your bulk quote request has been submitted successfully!
Please contact us if you have any questions.
Powered by Bioz
