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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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HSP90AB1 Antibody / Molecular Chaperone Antibody detects heat shock protein 90 beta, a constitutively expressed molecular chaperone that plays an essential role in protein folding, stabilization and quality control within the cytoplasm. Unlike the inducible HSP90AA1 isoform, HSP90AB1 is expressed under normal physiological conditions and supports the maturation and maintenance of a wide variety of client proteins involved in signal transduction, cell cycle regulation, apoptosis and intracellular trafficking. HSP90AB1 Antibody / Molecular Chaperone Antibody is widely used to investigate protein homeostasis, cellular stress responses and molecular chaperone biology.
HSP90AB1 functions as an ATP-dependent chaperone that cooperates with numerous co-chaperones to guide the folding, conformational stability and functional activity of newly synthesized and damaged proteins. Many kinases, transcription factors, hormone receptors and signaling molecules rely on HSP90AB1 for proper maturation and stability. Through these interactions, HSP90AB1 helps preserve proteome integrity while protecting cells from protein misfolding and aggregation during normal growth and environmental stress.
Because HSP90AB1 regulates numerous signaling pathways simultaneously, it has become an important research target in oncology, neuroscience and cell biology. Elevated HSP90 activity supports the stability of many oncogenic client proteins that promote tumor growth, survival, angiogenesis and metastasis. HSP90AB1 also contributes to neuroprotection, immune regulation and adaptation to cellular stress, making it valuable for investigations of neurodegenerative disease, inflammation and developmental biology. HSP90AB1 Antibody / Molecular Chaperone Antibody provides an effective tool for studying these diverse biological processes.
Specific detection of HSP90AB1 is particularly important because multiple HSP90 family members share substantial sequence similarity. Highly specific antibodies help distinguish HSP90AB1 from related isoforms, improving confidence in expression studies across normal tissues, cancer specimens and experimental models. This page features clone HSP90AB1/3951, a mouse monoclonal antibody that has been Protein Microarray Validated, providing additional confidence in target specificity for research applications.
NSJ Bioreagents offers HSP90AB1 Antibody / Molecular Chaperone Antibody products for researchers studying protein folding, molecular chaperone biology and cellular stress responses. These antibodies support applications including Western blot, immunohistochemistry, immunofluorescence and flow cytometry analysis of HSP90AB1 expression and localization. HSP90AB1 Antibody / Molecular Chaperone Antibody provides a valuable tool for investigating protein homeostasis, client protein regulation and disease-associated molecular chaperone pathways.
Explore additional oncology research tools in our Cancer Antibodies page, featuring antibodies against molecular chaperones, signaling proteins and other biomarkers involved in tumor progression, cellular stress responses and cancer biology.
Optimal dilution of the HSP90AB1 Antibody / Molecular Chaperone Antibody should be determined by the researcher.
A portion of amino acids 581-704 from the human protein was used as the immunogen for the HSP90AB1 antibody.
Store the HSP90AB1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Hsp90 beta antibody, Heat Shock Protein 90 Beta antibody, HSP90B antibody, HSP84 antibody, HSPCB antibody, HSP90 Beta Cytosolic antibody, HSP90AB1 protein antibody
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