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Home >> Antibodies >> HSP90 Antibody / HSP90AA1

HSP90 Antibody / HSP90AA1 [clone 803CT9.1.2] (F52639)

  Catalog No Formulation Size Price (USD)  
Image F52639-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F52639-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot analysis of lysate from (1) rat L6, (2) mouse NIH3T3, (3) T47D, (4) A2058, (5) HepG2, (6) K562, (7) HeLa cell line using HSP90 antibody at 1:1000.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, l
Clone Name 803CT9.1.2
Purity Purified
UniProt P07900
Applications Western blot : 1:1000
Limitations This HSP90 antibody is available for research use only.
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Description

Heat Shock Protein 90 is a molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. [UniProt]

Application Notes

Titration of the HSP90 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids from 150-400 of the human protein were used as the immunogen for this HSP90AA1 antibody.

Storage

Aliquot the HSP90 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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