- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
HSP70 Antibody / HSPA1A / HSPA1B (F54222)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F54222-0.2ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.2 ml | 399 | |
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F54222-0.05ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.05 ml | 185 |
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| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse, Rat |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity |
| UniProt | P0DMV8 |
| Localization | Nuclear, cytoplasmic |
| Applications | Western blot : 1:1000 |
| Limitations | This HSP70 antibody is available for research use only. |
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In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
Optimal dilution of the HSP70 antibody should be determined by the researcher.
An amino acid sequence surrounding Y41 of human HSPA1A/B was used as the immunogen for the HSP70 antibody.
Aliquot the HSP70 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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