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Home >> Antibodies >> hSET1 Antibody / SET1 / SETD1A

hSET1 Antibody / SET1 / SETD1A (RQ6008)

  Catalog No Formulation Size Price (USD)  
Image RQ6008 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of human 1) SW620 and 2) U-87 MG lysate with hSET1 antibody. Predicted molecular weight ~186 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt O15047
Localization Nuclear
Applications Western blot : 0.5-1ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This hSET1 antibody is available for research use only.
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Description

Histone-lysine N-methyltransferase SETD1A is an enzyme that in humans is encoded by the SETD1A gene. It is mapped to 16p11.2. The protein encoded by this gene is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. Trimethylation of histone H3 at lysine 4 (H3K4me3) is a chromatin modification known to generally mark the transcription start sites of active genes. The protein contains SET domains, a RNA recognition motif domain and is a member of the class V-like SAM-binding methyltransferase superfamily.

Application Notes

Optimal dilution of the hSET1 antibody should be determined by the researcher.

Immunogen

Recombinant human protein (amino acids D8-K153) was used as the immunogen for the hSET1 antibody.

Storage

After reconstitution, the hSET1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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