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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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HSD17B13 Antibody / SCDR9 Antibody recognizes hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13), a member of the short-chain dehydrogenase/reductase family that is strongly associated with hepatic lipid metabolism. HSD17B13 is enriched in the liver and localizes prominently to lipid droplets, intracellular organelles involved in the storage and mobilization of neutral lipids. Its localization and enzymatic characteristics have made HSD17B13 an important target in studies of hepatic metabolism and lipid-associated liver biology.
HSD17B13 contains structural features characteristic of short-chain dehydrogenase/reductase enzymes and has been investigated for activities involving lipid and steroid-related substrates. The protein is associated with lipid droplets through an N-terminal hydrophobic region, positioning it at an important interface between intracellular lipid storage and metabolic regulation. Changes in HSD17B13 expression or activity may therefore influence hepatic lipid handling and metabolic homeostasis.
Human genetic studies have generated substantial interest in HSD17B13 because loss-of-function variants have been associated with reduced risk of progression in several forms of chronic liver disease. These observations have linked HSD17B13 biology to metabolic dysfunction-associated steatotic liver disease, alcohol-associated liver disease, hepatic inflammation, fibrosis, and other processes involved in liver injury. The relationship between HSD17B13 activity and disease progression has also made the protein an important target in therapeutic research focused on chronic liver disorders.
This HSD17B13 Antibody provides a reagent for investigating the expression and biology of this liver-enriched lipid droplet protein. NSJ Bioreagents offers this SCDR9 Antibody for researchers studying hepatic metabolism, lipid droplet biology, metabolic liver disease, and pathways associated with liver injury and disease progression. An HSD17B13 Antibody can support research into the molecular relationship between lipid metabolism, hepatic cellular function, and chronic liver disease.
Explore our Metabolism Antibodies page for additional reagents targeting proteins involved in lipid metabolism, nutrient processing, energy homeostasis, and metabolic regulation.
Optimal dilution of the HSD17B13 Antibody / SCDR9 Antibody should be determined by the researcher.
An E.coli-derived human recombinant protein (amino acids R59-K300) was used as the immunogen for the HSD17B13 antibody.
After reconstitution, the HSD17B13 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
HSD17B13 antibody, SCDR9 antibody, Hydroxysteroid 17-beta dehydrogenase 13 antibody, 17-beta-HSD 13 antibody, DHB13 antibody
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