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Home >> Antibodies >> HPV-16 L1 Antibody

HPV-16 L1 Antibody [clone HPV16L1/1058] (V3086CF488)

  Catalog No Formulation Size Price (USD)  
Image V3086CF488-100T 500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 Tests 519
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Availability 1-3 business days
Species Reactivity Type 16 of Human Papilloma Virus (HPV-16).
Format CF488 Conjugate
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2a, kappa
Clone Name HPV16L1/1058
Purity Protein G affinity chromatography
UniProt P03101
Localization Nuclear
Applications Flow cytometry : 5ul per test per one 10^6 cells in 0.1ml or 5ul per 100ul of whole blood
Immunofluorescence : 1-2ug/ml
Limitations This HPV-16 L1 antibody is available for research use only.
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Description

Reacts with a protein of 57kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

Application Notes

Optimal dilution of the HPV-16 L1 antibody should be determined by the researcher.

Immunogen

Human papilloma virus type 16, major capsid protein L1, was used as the immunogen for the HPV-16 L1 antibody.

Storage

Store the HPV-16 L1 antibody at 2-8oC, protected from light.

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