- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
HOXA10 Antibody Biotin Conjugate (R35106BTN)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
R35106BTN | 0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide | 100 ug | 475 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Predicted Reactivity | Cow, Mouse, Pig |
| Format | Biotin Conjugate |
| Host | Goat |
| Clonality | Polyclonal (goat origin) |
| Isotype | Goat Ig |
| Purity | Antigen affinity |
| UniProt | P31260 |
| Gene ID | 3206 |
| Applications | Western Blot : 0.2-0.6ug/ml Immunohistochemistry (FFPE) : 5ug/ml ELISA (peptide) LOD : 1:32000 |
| Limitations | This HOXA10 antibody is available for research use only. |
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HOXA10 Antibody Biotin Conjugate recognizes HOXA10, a highly conserved homeobox transcription factor that regulates embryonic development, anterior-posterior body patterning, and tissue differentiation. HOXA10 functions as a sequence-specific DNA-binding protein that controls the expression of genes involved in organogenesis, morphogenesis, and cellular lineage specification. In addition to its essential developmental roles, HOXA10 contributes to adult tissue homeostasis by regulating stem cell function, endometrial receptivity, and reproductive tract development. Biotin conjugation enables sensitive detection of HOXA10 in biotin-streptavidin-based immunoassays while preserving the antibody's specificity for its target protein.
HOXA10 is expressed in multiple tissues during embryogenesis and remains active in selected adult tissues, particularly within the reproductive system, hematopoietic compartment, and mesenchymal cell populations. Tight spatial and temporal regulation of HOXA10 expression is required for normal tissue development and differentiation, whereas altered expression has been linked to infertility, endometriosis, leukemia, ovarian cancer, endometrial carcinoma, and other malignancies. As a master regulator of developmental transcriptional programs, HOXA10 continues to be widely investigated in developmental biology, stem cell research, reproductive medicine, and oncology. HOXA10 Antibody Biotin Conjugate is well suited for applications requiring sensitive detection of HOXA10 through biotin-streptavidin amplification systems, including immunohistochemistry, immunocytochemistry, ELISA, and other affinity-based assays.
Explore our HOXA10 Antibody / Developmental Transcription Factor Antibody page to learn more about this key regulator of embryonic development, tissue differentiation, and developmental gene expression.
Optimal dilution of the HOXA10 antibody should be determined by the researcher.
Amino acids PQATSCSFAQNIKE were used as the immunogen for this HOXA10 antibody.
Aliquot and store the HOXA10 antibody at -20oC.
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