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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Heme oxygenase (decycling) 1, also known as HO-1, is an essential enzyme in heme catabolism. HO-1 belongs to the heme oxygenase family. The HMOX1 gene is located on the long (q) arm of chromosome 22 at position 12.3, from base pair 34,101,636 to base pair 34,114,748. HO-1, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. HO-1 activity is induced by its substrate heme and by various nonheme substances.
The stated application concentrations are suggested starting amounts. Titration of the HO-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Human partial recombinant protein (AA 1-288) was used as the immunogen for this HO-1 antibody.
After reconstitution, the HO-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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