HMGCS1 Antibody (R36419)

HMGCS1 Antibody Multi-Cell Line WB. Western blot analysis of A) HeLa, B) HepG2, and C) K562 cell lysates using HMGCS1 Antibody. A distinct immunoreactive band is detected at approximately 57 kDa in all three cell lines, consistent with the predicted molecular weight of HMGCS1 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 1). HMGCS1 is a key cytosolic enzyme of the mevalonate pathway that catalyzes the synthesis of HMG-CoA, an essential precursor for cholesterol and isoprenoid biosynthesis. The consistent detection of a single band across multiple human cell lines supports specific recognition of endogenous HMGCS1 and demonstrates the utility of this antibody for western blot applications. Predicted molecular weight: ~57 kDa. Observed molecular weight: ~57 kDa.