- Tel: 858.663.9055
- Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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HMGA1 encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus.
Titration of the HMGA1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 64-93 from the human protein was used as the immunogen for this HMGA1 antibody.
Aliquot the HMGA1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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