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Home >> Antibodies >> HLA-ABC Antibody (MHC I)

HLA-ABC Antibody (MHC I) [clone SPM419] (V8847)

  Catalog No Formulation Size Price (USD)  
Image V8847-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V8847-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V8847SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Bulk quote request
SDS-PAGE analysis of purified, BSA-free HLA-ABC antibody (clone SPM419) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2a, kappa
Clone Name SPM419
Purity Protein A/G affinity
UniProt P01889 , P30443 , P30499
Localization Cell surface
Applications Flow cytometry : 1-2ug/million cells
Western blot : 1-2ug/ml
Limitations This HLA-ABC antibody is available for research use only.
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Description

Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.

Application Notes

Optimal dilution of the HLA-ABC antibody should be determined by the researcher.

Immunogen

Human peripheral blood leukocytes were used as the immunogen for the HLA-ABC antibody.

Storage

Aliquot the HLA-ABC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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