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Home >> Antibodies >> Histone H4 Antibody / HIST1H4A

Histone H4 Antibody / HIST1H4A (F55056)

  Catalog No Formulation Size Price (USD)  
Image F55056-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 439
Image
F55056-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 205
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Western blot analysis of 1) human HL60, 2) mouse NIH 3T3, 3) human HeLa, 4) human A431, 5) rat H-4-II-E and 6) rat C6 cell lysate using Histone H4 antibody at 1:2000.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Predicted Reactivity All species
Format Antigen affinity purified
Host Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P62805
Applications Western Blot : 1:2000
Limitations This Histone H4 antibody is available for research use only.
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Description

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Application Notes

Titration of the Histone H4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This Histone H4 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 71-103 amino acids from the C-terminal region of human HIST1H4A.

Storage

Aliquot the Histone H4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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