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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Titration of the Histone H3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
This Histone H3 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 8~39 amino acids from human.
Aliquot the Histone H3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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