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Home >> Antibodies >> Histone H3 Antibody

Histone H3 Antibody (F52121)

  Catalog No Formulation Size Price (USD)  
Image F52121-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F52121-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Histone H3 antibody western blot analysis in HeLa lysate.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Bovine, C. elegans, Chicken, Drosophila, Mouse, Pig, Rat, Xenopus, Zebrafish
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P68431
Applications Western blot : 1:1000
Limitations This Histone H3 antibody is available for research use only.
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Description

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Application Notes

Titration of the Histone H3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 28-57 from the human protein was used as the immunogen for this Histone H3 antibody.

Storage

Aliquot the Histone H3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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