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- Tel: 858.663.9055
- Email: info@nsjbio.com
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq].
The stated application concentrations are suggested starting points. Titration of the HIST1H2BJ antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 57-86 from the human protein was used as the immunogen for the HIST1H2BJ antibody.
Aliquot the HIST1H2BJ antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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