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Home >> Antibodies >> HIF1A Antibody

HIF1A Antibody [clone 288CT11.7.1] (F53560)

  Catalog No Formulation Size Price (USD)  
Image F53560-0.1ML In ascites with 0.09% sodium azide 0.1 ml 399
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HIF1A antibody western blot analysis in U251 lysate. Routinely observed molecular weight: 100~120 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Ascites
Clonality Monoclonal (mouse origin)
Isotype Mouse IgM, k
Clone Name 288CT11.7.1
Purity Ascites
UniProt Q16665
Localization Nuclear, possible cytoplasmic
Applications Western blot : 1:100-1:1000
Limitations This HIF1A antibody is available for research use only.
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Description

Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified.

Application Notes

Titration of the HIF1A antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This HIF1A antibody was produced from mouse immunized with HIF1A recombinant protein.

Storage

Aliquot the HIF1A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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