- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
HFE Antibody (Hereditary hemochromatosis protein) (R32770)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
R32770 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 429 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Purity | Antigen affinity |
| Buffer | Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide |
| UniProt | Q30201 |
| Applications | Western Blot : 0.5-1ug/ml |
| Limitations | This HFE antibody is available for research use only. |
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Human hemochromatosis protein, also known as HFE, is a protein which in humans is encoded by the HFE gene. The gene is located on short arm of chromosome 6 at location 6p21.3. It is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene.
Optimal dilution of the HFE antibody should be determined by the researcher.
Amino acids Q82-R199 from the human protein were used as the immunogen for the HFE antibody.
After reconstitution, the HFE antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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