- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Hes1 Antibody (F52879)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F52879-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
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F52879-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
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| Availability | 1-3 business days |
| Species Reactivity | Mouse |
| Predicted Reactivity | Bovine, Human, Rat, Xenopus |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity |
| UniProt | P35428 |
| Applications | Western blot : 1:1000 |
| Limitations | This Hes1 antibody is available for research use only. |
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Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (By similarity). Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross- link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity).
Titration of the Hes1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
This mouse Hes1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 102-137 amino acids from the Central region of mouse Hes1.
Aliquot the Hes1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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