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Home >> Antibodies >> HER2 Antibody ErbB2

HER2 Antibody ErbB2 [clone HRB2/273] (V2378)

  Catalog No Formulation Size Price (USD)  
Image V2378-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 429
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V2378-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 199
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V2378SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 429
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name HRB2/273
Purity Protein G affinity chromatography
Buffer 1X PBS, pH 7.4
Gene ID 2064 (Human)
Localization Extracellular/Intracellular cell membrane (this mAb is binds to the extracellular portion of the protein)
Applications ELISA (order BSA/sodium azide-free format for coating) :
Flow cytometry : 1-2ug/10^6 cells
Immunofluorescence : 1-2ug/ml
Limitations This HER2 / ErbB2 antibody is available for research use only.
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Description

This antibody recognizes a protein of 185kDa, which is identified as HER2 / ErbB2. Its epitope is localized in the extracellular domain. HER2 is a member of the EGFR family. This antibody is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. HER2 / ErbB2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.

Application Notes

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.
1. This HER2 antibody binds to the extracellular/cell surface region of the protein.

Immunogen

Recombinant human HER2 protein was used as the immunogen for this antibody.(1)

Storage

Store the HER2 / ErbB2 antibody at 2-8°C.

Alternate Names

p185, CD340, Verb b2 Erythroblastic Leukemia Viral Oncogene Homolog 2, ErbB2 antibody, Neuro/Glioblastoma Derived Oncogene Homolog, HER2 antibody

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