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Home >> Antibodies >> H4 Antibody / Histone H4

H4 Antibody / Histone H4 (F49271)

  Catalog No Formulation Size Price (USD)  
Image F49271-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F49271-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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H4 antibody western blot analysis in (1) human K562 and (2) mouse NIH3T3 lysate.
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P62805
Applications Western blot : 1:1000
Limitations This H4 antibody is available for research use only.
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Description

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.

Application Notes

Titration of the H4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 1-30 from the human protein was used as the immunogen for this H4 antibody.

Storage

Aliquot the H4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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