- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
H2AFX Antibody / Histone H2AX [clone BIA-8] (RQ5464)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ5464 | Antibody in PBS with 0.02% sodium azide and 50% glycerol | 100 ul | 429 |
| Availability | 1-2 weeks |
| Species Reactivity | Human, Mouse, Rat |
| Format | Purified |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | BIA-8 |
| Purity | Affinity purified |
| UniProt | P16104 |
| Localization | Nuclear |
| Applications | Western blot : 1:500-1:2000 Immunohistochemistry : 1:50-1:200 |
| Limitations | This H2AFX antibody is available for research use only. |
|
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [RefSeq]
Optimal dilution of the H2AFX antibody should be determined by the researcher.
A synthetic peptide specific to human Histone H2A.X / H2AFX was used as the immunogen for the H2AFX antibody.
Store the H2AFX antibody at -20oC.
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