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Home >> Antibodies >> GSN Antibody / Gelsolin

GSN Antibody / Gelsolin (F54920)

  Catalog No Formulation Size Price (USD)  
Image F54920-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 429
Image
F54920-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 199
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Flow cytometry testing of human A375 cells with GSN antibody; Blue=isotype control, Green= GSN antibody.
IHC testing of FFPE human skeletal muscle tissue with GSN antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
Western blot testing of 1) human plasma, 2) human HeLa, 3) mouse spleen and 4) rat kidney lysate with GSN antibody. Predicted molecular weight: 81-86 kDa (multiple isoforms).
Western blot testing of human MCF7 cell lysate with GSN antibody. Predicted molecular weight: 81-86 kDa (multiple isoforms).
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt P06396
Localization Cytoplasmic, secreted
Applications Western Blot : 1:1000-1:2000
Flow Cytometry : 1:10-1:50 (1x10e6 cells)
Immunohistochemistry (FFPE) : 1:50-1:100
Limitations This GSN antibody is available for research use only.
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Description

GSN binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this protein are a cause of familial amyloidosis Finnish type (FAF).

Application Notes

The stated application concentrations are suggested starting points. Titration of the GSN antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 230-259 from the human protein was used as the immunogen for the GSN antibody.

Storage

Aliquot the GSN antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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