- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
GSK3B Antibody (F51046)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F51046-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
|
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F51046-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity |
| UniProt | P49841 |
| Applications | Western blot : 1:1000 IHC (Paraffin) : 1:50-1:100 |
| Limitations | This GSK3B antibody is available for research use only. |
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GSK3B is a constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1. May also mediate the development of insulin resistance by regulating activation of transcription factors. [UniProt]
Titration of the GSK3B antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 4-34 from the human protein was used as the immunogen for this GSK3B antibody.
Aliquot the GSK3B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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