- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Granzyme B Antibody [clone AAHC-7] (RQ5315)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ5315 | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA | 100 ul | 429 |
|
| Availability | 1-2 weeks |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | AAHC-7 |
| Purity | Affinity purified |
| UniProt | P10144 |
| Applications | Immunohistochemistry (FFPE) : 1:50-1:200 |
| Limitations | This Granzyme B antibody is available for research use only. |
|
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This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Optimal dilution of the Granzyme B antibody should be determined by the researcher.
A synthetic peptide specific to human Granzyme B / GZMB was used as the immunogen for the Granzyme B antibody.
Store the Granzyme B antibody at -20oC.
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