- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
GRAMD4 Antibody / Apoptosis Regulation Marker [clone PCRP-GRAMD4-1A10] (V9499)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
V9499-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 559 | |
|
|
V9499-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 20 ug | 259 | |
|
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V9499SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Host | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1 |
| Clone Name | PCRP-GRAMD4-1A10 |
| Purity | Protein A/G affinity |
| UniProt | Q6IC98 |
| Localization | Cytoplasm |
| Applications | Flow Cytometry : 1-2ug/million cells Immunofluorescence : 1-2ug/ml |
| Limitations | This GRAMD4 Antibody / Apoptosis Regulation Marker is available for research use only. |
|
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GRAM domain-containing protein 4 (GRAMD4) is a regulatory protein involved in apoptosis-associated signaling pathways, mitochondrial membrane regulation, and p53-mediated cellular stress responses. GRAMD4 Antibody / Apoptosis Regulation Marker is suitable for investigations involving mitochondrial signaling pathways, programmed cell death mechanisms, and stress-associated transcriptional regulation. GRAMD4 has been implicated in pathways controlling apoptotic signaling and cellular responses to genotoxic stress and differentiation-associated signaling environments.
GRAMD4 antibody, also referred to as GRAM domain-containing protein 4 antibody, Death-inducing p53 target protein 1 antibody, DIP1 antibody, and Mitochondrial apoptosis protein antibody in the literature, recognizes a regulatory protein associated with mitochondrial apoptotic signaling pathways. GRAMD4 expression has been linked to p53-responsive transcriptional programs and apoptosis-associated cellular signaling mechanisms. Through regulation of mitochondrial-associated pathways, GRAMD4 contributes to programmed cell death signaling and stress-associated cellular homeostasis networks.
Proteins involved in apoptosis regulation and mitochondrial signaling are central components of pathways controlling proliferation, survival, differentiation, and cellular stress adaptation. GRAMD4 has been investigated in studies involving tumor suppression pathways, p53-associated transcriptional responses, and mitochondrial apoptotic regulation. Because mitochondrial signaling proteins participate in broader cellular stress-response mechanisms, GRAMD4 remains relevant for investigations involving cancer biology, apoptosis-associated transcriptional regulation, and cellular response pathways linked to DNA damage and stress signaling.
GRAMD4 additionally contains a GRAM domain associated with membrane-interacting signaling proteins involved in intracellular regulatory pathways. Members of the GRAM domain-containing protein family have been implicated in membrane-associated signaling events, organelle regulation, and stress-responsive cellular pathways. Through interactions with mitochondrial and apoptosis-associated signaling networks, GRAMD4 contributes to regulation of cell fate-associated transcriptional and intracellular signaling programs.
Flow cytometry analysis supports detection of endogenous GRAMD4 expression in human cells. HuProt(TM) protein microarray specificity validation with clone PCRP-GRAMD4-1A10 further demonstrates highly selective recognition of GRAMD4 among more than 19,000 full-length human proteins. The combined validation profile supports use of this mouse monoclonal antibody for investigations involving apoptosis signaling, mitochondrial regulatory proteins, p53-associated pathways, and stress-responsive cellular signaling mechanisms.
An antibody targeting GRAMD4 can therefore support studies involving programmed cell death pathways, mitochondrial signaling regulation, stress-associated transcriptional responses, apoptosis-associated cellular biology, and p53-mediated signaling networks.
GRAMD4 participates in mitochondrial apoptosis signaling and stress-associated cellular regulatory pathways; explore related signaling and regulatory proteins on our Signal Transduction Antibodies landing page.
Optimal dilution of the GRAMD4 Antibody / Apoptosis Regulation Marker should be determined by the researcher.
Recombinant full-length human GRAMD4 protein was used as the immunogen for the GRAMD4 antibody.
Aliquot the GRAMD4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
GRAMD4 antibody, GRAM domain-containing protein 4 antibody, Death-inducing p53 target protein 1 antibody, DIP1 antibody, Mitochondrial apoptosis protein antibody
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