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Home >> Antibodies >> GPX3 Antibody

GPX3 Antibody (F54583)

  Catalog No Formulation Size Price (USD)  
Image F54583-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F54583-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot testing of 1) human kidney, 2) human plasma, 3) mouse kidney, 4) mouse plasma and 5) rat kidney lysate with GPX3 antibody. Expected molecular weight: 23-26 kDa.
Western blot testing of mouse plasma lysate with GPX3 antibody. Expected molecular weight: 23-26 kDa.
IHC testing of FFPE human kidney tissue with GPX3 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity purified
UniProt P22352
Localization Cytoplasmic, nuclear
Applications Western blot : 1:500-1:2000
Immunohistochemistry (FFPE) : 1:25
Limitations This GPX3 antibody is available for research use only.
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Related Products

  • Applications : WB, IHC, ELISA (peptide)
    Reactivity : Human, Mouse, Pig
    Pred. Reactivity : Rat, Dog

Description

This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.

Application Notes

The stated application concentrations are suggested starting points. Titration of the GPX3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 93-123 from the human protein was used as the immunogen for the GPX3 antibody.

Storage

Aliquot the GPX3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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