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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
GNG4 Antibody for WB / G Protein Gamma 4 Western Blot Antibody [clone 7B6] (RQ6992)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
RQ6992 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 449 |
|
| Availability | 1-3 business days |
| Species Reactivity | Mouse, Rat |
| Format | Antigen affinity purified |
| Host | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1 |
| Clone Name | 7B6 |
| Purity | Antigen affinity purified |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| UniProt | P50150 |
| Applications | Western Blot : 0.5-1 ug/ml |
| Limitations | This GNG4 antibody is available for research use only. |
|
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G protein subunit gamma 4 (GNG4) is a membrane-associated signaling protein that functions within the heterotrimeric G protein complex to regulate G protein-coupled receptor pathways. The GNG4 Antibody for WB is specifically developed for western blot applications, enabling reliable detection of GNG4 in denatured protein lysates and supporting studies focused on protein size, expression levels, and signaling pathway analysis.
GNG4 antibody for WB, also known as G Protein Gamma 4 antibody or Guanine nucleotide-binding protein subunit gamma-4 antibody, recognizes a small gamma subunit that forms the G beta-gamma complex and directly regulates downstream effectors including ion channels, MAPK signaling components, and phospholipase pathways. Its small molecular weight and membrane association make western blot analysis particularly important for confirming band specificity and resolving GNG4 from other gamma subunits.
This mouse monoclonal GNG4 Antibody for WB was generated against a human peptide sequence immunogen, providing defined epitope recognition and consistent band detection in western blot assays. Peptide-derived monoclonal antibodies are especially valuable in WB workflows due to their ability to produce sharp, well-defined bands with reduced background. Western blot testing shows clear detection of GNG4 in mouse and rat brain lysates, consistent with its known enrichment in neuronal tissues and GPCR-driven signaling environments.
GNG4 localizes to the cytoplasmic face of the plasma membrane, where it stabilizes G beta subunits and facilitates receptor-mediated signaling. It is expressed in neural tissues, immune cells, and epithelial compartments, with increasing interest in its role in tumor biology, including glioma progression and colorectal cancer signaling networks. Western blot analysis of GNG4 is widely used to study these pathways due to the proteinâs small size and involvement in dynamic signaling complexes.
A mouse monoclonal GNG4 Antibody for WB is suitable for detecting GNG4 protein expression in western blot experiments requiring high specificity, clean band resolution, and reproducible results across species such as mouse and rat. This format is particularly well suited for studies of GPCR signaling, neuronal protein expression, and comparative protein analysis in research settings.
Optimal dilution of the GNG4 Antibody for WB / G Protein Gamma 4 Western Blot Antibody should be determined by the researcher.
Recombinant human protein (amino acids M1-D52) was used as the immunogen for the GNG4 Antibody for WB / G Protein Gamma 4 Western Blot Antibody.
After reconstitution, the GNG4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
G Protein Gamma 4 antibody, Guanine nucleotide binding protein gamma 4 antibody, G gamma 4 antibody, GNG4 protein antibody
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