- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Glycoprotein 2 Antibody / GP2 / ZAP75 [clone GP2/3133R] (V4410)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
V4410-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 519 | |
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V4410-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 20 ug | 229 | |
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V4410SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 519 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG, kappa |
| Clone Name | GP2/3133R |
| Purity | Protein A/G affinity |
| UniProt | P55259 |
| Localization | Cell surface, Secreted, Cytoplasmic |
| Applications | ELISA : 2-4mg/ml for coating (order BSA-free format) |
| Limitations | This Glycoprotein 2 antibody is available for research use only. |
|
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GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.
Optimal dilution of the Glycoprotein 2 antibody should be determined by the researcher.
A recombinant fragment of human protein (within amino acids 35-179) was used as the immunogen for the Glycoprotein 2 antibody.
Aliquot the Glycoprotein 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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