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Home >> Antibodies >> Glutaredoxin 3 Antibody / GLRX3 / TXNL2

Glutaredoxin 3 Antibody / GLRX3 / TXNL2 (F54635)

  Catalog No Formulation Size Price (USD)  
Image F54635-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F54635-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot testing of mouse bladder tissue lysate with Glutaredoxin 3 antibody. Predicted molecular weight ~37 kDa.
Western blot testing of human 1) HepG2 and 2) Raji cell lysate with Glutaredoxin 3 antibody. Predicted molecular weight ~37 kDa.
Flow cytometry testing of human HepG2 cells with Glutaredoxin 3 antibody; Blue=isotype control, Green= Glutaredoxin 3 antibody.
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity purified
UniProt O76003
Localization Cytoplasmic
Applications Flow cytometry : 1:25 (1x10e6 cells)
Western blot : 1:500-1:2000
Limitations This Glutaredoxin 3 antibody is available for research use only.
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  • Applications : WB
    Reactivity : Human, Mouse, Rat

Description

GLRX3 is a critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity.

Application Notes

The stated application concentrations are suggested starting points. Titration of the Glutaredoxin 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 81-110 from the human protein was used as the immunogen for the Glutaredoxin 3 antibody.

Storage

Aliquot the Glutaredoxin 3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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