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Home >> Antibodies >> Glutamine Synthetase Antibody

Glutamine Synthetase Antibody [clone CCH-7] (RQ5441)

  Catalog No Formulation Size Price (USD)  
Image RQ5441 Antibody in PBS with 0.02% sodium azide and 50% glycerol 100 ul 429
Microvalidated Rab Mono Image
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Western blot testing of human 1) Jurkat and 2) HeLa cell lysate with Glutamine Synthetase antibody. Predicted molecular weight ~42 kDa.
IHC staining of FFPE human liver with Glutamine Synthetase antibody. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name CCH-7
Purity Affinity purified
UniProt P15104
Localization Cytoplasmic
Applications Western blot : 1:500-1:2000
Immunohistochemistry (FFPE) : 1:50-1:200
Limitations This Glutamine Synthetase antibody is available for research use only.
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Description

The protein encoded by the GLUL gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. [RefSeq]

Application Notes

Optimal dilution of the Glutamine Synthetase antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human Glutamine Synthetase / GLUL was used as the immunogen for the Glutamine Synthetase antibody.

Storage

Store the Glutamine Synthetase antibody at -20oC.

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