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Home >> Antibodies >> GFAP Antibody / Glial Fibrillary Acidic Protein

GFAP Antibody / Glial Fibrillary Acidic Protein [clone ECO-7] (RQ5420)

  Catalog No Formulation Size Price (USD)  
Image RQ5420 Antibody in PBS with 0.02% sodium azide and 50% glycerol 100 ul 429
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Western blot testing of rat brain lysate with GFAP antibody. Predicted molecular weight ~50 kDa.
IHC staining of FFPE human glioma with GFAP antibody. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.
Availability 1-2 weeks
Species Reactivity Human, Rat
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name ECO-7
Purity Affinity purified
UniProt P14136
Localization Cytoplasmic
Applications Western blot : 1:500-1:2000
Immunohistochemistry (FFPE) : 1:50-1:200
Limitations This GFAP antibody is available for research use only.
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Description

This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [RefSeq]

Application Notes

Optimal dilution of the GFAP antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human GFAP was used as the immunogen for the GFAP antibody.

Storage

Store the GFAP antibody at -20oC.

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