Gephyrin Antibody / Inhibitory Synapse and Receptor Clustering Marker Antibody (RQ6558)

Gephyrin Antibody A431 IF. Immunofluorescence analysis of FFPE human A431 cells using Gephyrin antibody (red) shows punctate cytoplasmic staining consistent with Gephyrin localization in receptor clustering and inhibitory synaptic scaffold-associated structures, while nuclei are counterstained with DAPI (blue). HIER: steam sections in pH6 citrate buffer for 20 min.

Gephyrin Antibody Papillary Thyroid Carcinoma IHC. Immunohistochemistry of FFPE human papillary thyroid carcinoma tissue using Gephyrin antibody shows HRP-DAB brown cytoplasmic and membranous staining in tumor epithelial cells, consistent with Gephyrin expression in receptor clustering and synaptic scaffold-associated signaling structures, while surrounding stromal elements display lower background. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

Gephyrin Antibody Stomach Cancer IHC. Immunohistochemistry of FFPE human stomach carcinoma tissue using Gephyrin antibody shows granular HRP-DAB brown cytoplasmic staining in tumor cells, consistent with Gephyrin-associated receptor clustering and inhibitory signaling scaffold localization, while surrounding stromal regions display lower background. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

Gephyrin Antibody Liver Cancer IHC. Immunohistochemistry of FFPE human liver carcinoma tissue using Gephyrin antibody shows diffuse HRP-DAB brown cytoplasmic staining in tumor cells, consistent with Gephyrin-associated receptor clustering and inhibitory signaling scaffold organization, while surrounding stromal elements display lower background. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

Gephyrin Antibody Mouse Brain IHC. Immunohistochemistry of FFPE mouse brain tissue using Gephyrin antibody shows diffuse and punctate HRP-DAB brown cytoplasmic staining in neuronal cell populations, consistent with Gephyrin localization at inhibitory synapses and postsynaptic receptor clustering structures within neural tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

Gephyrin Antibody Rat Brain IHC. Immunohistochemistry of FFPE rat brain tissue using Gephyrin antibody demonstrates punctate HRP-DAB brown cytoplasmic staining in neuronal cells, consistent with Gephyrin-associated inhibitory synapse organization and receptor scaffold localization in brain tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

Gephyrin Antibody Rat Lung IHC. Immunohistochemistry of FFPE rat lung tissue using Gephyrin antibody shows HRP-DAB brown cytoplasmic staining in epithelial cell populations, consistent with Gephyrin-associated receptor clustering and scaffold protein localization, while surrounding stromal regions display lower background. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

Gephyrin Antibody Multi-Species WB. Western blot analysis of 1) human HeLa, 2) human HepG2, 3) human A549, 4) monkey COS-7, 5) human Jurkat, 6) rat brain, 7) mouse brain, 8) mouse kidney, 9) mouse lung, and 10) mouse Neuro-2a cell lysates using Gephyrin antibody detects a prominent band at approximately 90-95 kDa across multiple samples, consistent with the commonly observed apparent molecular weight of Gephyrin despite a predicted molecular weight of approximately 80-83 kDa. The broad detection profile supports Gephyrin expression in neuronal and non-neuronal tissues and is consistent with its role in inhibitory synapse organization and receptor clustering.