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- Tel: 858.663.9055
- Email: info@nsjbio.com
This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.
Titration of the GCNT2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 364-391 from the human protein was used as the immunogen for this GCNT2 antibody.
Aliquot the GCNT2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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