- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Galactosidase alpha Antibody / Gla (F54879)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F54879-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
|
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F54879-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Purified |
| UniProt | P06280 |
| Localization | Cytoplasmic |
| Applications | Flow cytometry : 1:10-1:50 (1x10e6 cells) Immunofluorescence : 1:10-1:50 Immunohistochemistry (FFPE) : 1:10-1:50 Western blot : 1:500-1:1000 |
| Limitations | This Galactosidase alpha antibody is available for research use only. |
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GLA is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.
The stated application concentrations are suggested starting points. Titration of the Galactosidase alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 83-112 from the human protein was used as the immunogen for the Galactosidase alpha antibody.
Aliquot the Galactosidase alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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