• Tel: 858.663.9055
  • SeparatorEmail: info@nsjbio.com
  • Tel: 858.663.9055
  • Email: info@nsjbio.com
Order
Home >> Antibodies >> GADD153 Antibody / CHOP / DDIT3

GADD153 Antibody / CHOP / DDIT3 (F54233)

NSJ bio Image Pdf Image
  Catalog No Formulation Size Price (USD)  
Image F54233-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F54233-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
Bulk quote request
Western blot testing of human PC-3 cell lysate with GADD153 antibody. Expected molecular weight: 19-29 kDa.
›
Western blot testing of human PC-3 cell lysate with GADD153 antibody. Expected molecular weight: 19-29 kDa.
Western blot testing of human skeletal muscle lysate with GADD153 antibody. Expected molecular weight: 19-29 kDa.
Immunofluorescent staining of fixed and permeabilized human HeLa cells with GADD153 antibody (green) and anti-Actin (red).
Flow cytometry testing of fixed and permeabilized human HeLa cells with GADD153 antibody; Blue=isotype control, Green= GADD153 antibody.
Flow cytometry testing of fixed and permeabilized human HEK293 cells with GADD153 antibody; Blue=isotype control, Green= GADD153 antibody.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity purified
UniProt P35638
Gene ID 1649
Localization Nuclear, cytoplasmic
Applications Western blot : 1:1000-1:2000
Flow cytometry : 1:25 (1x10e6 cells)
Immunofluorescence : 1:25
Limitations This GADD153 antibody is available for research use only.
Review this product on BioCompare and get a $20 Amazon gift card

Related Products

Description

This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.

Application Notes

The stated application concentrations are suggested starting points. Titration of the GADD153 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 120-149 from the human protein were used as the immunogen for the GADD153 antibody.

Storage

Aliquot the GADD153 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Related Products

   1.   View all DDIT3 antibodies

Cross
Bulk Quote Request Form
Name*:
Organization*:
Email*:
Phone Number*:
Catalog No.*:
Comments and Specifics(amount, formulation, etc.)*:
Validation code: Captchapackage Image


Can't read the image? click here to refresh.
    *required field

Your bulk quote request has been submitted successfully!

Please contact us if you have any questions.