FTL Antibody Biotin Conjugate / Ferritin Nanocage Protein Antibody [clone FTL/1386] (V3351BTN)

FTL Antibody Biotin Conjugate Kidney IHC. Immunohistochemistry analysis of FFPE human kidney tissue stained with FTL Antibody Biotin Conjugate demonstrates strong granular cytoplasmic HRP-DAB brown staining throughout renal tubular epithelial cell populations, consistent with expression of ferritin light chain / FTL in metabolically active nephron-associated compartments. This ferritin nanocage protein antibody highlights intracellular ferritin-associated iron sequestration pathways and oxidative stress-responsive cellular regulation within renal epithelium. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.

FTL Antibody Biotin Conjugate Renal Tubule IHC. Immunohistochemistry analysis of FFPE human kidney tissue stained with FTL Antibody Biotin Conjugate demonstrates diffuse granular cytoplasmic HRP-DAB brown staining throughout renal tubular epithelial structures, consistent with expression of ferritin light chain / FTL in metabolically active tubular compartments involved in ferritin nanocage organization and intracellular iron sequestration. This ferritin nanocage protein antibody highlights ferritin-associated oxidative stress-responsive pathways within renal epithelial tissue. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.

Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using FTL antibody. These results demonstrate the foremost specificity of the FTL/1386 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.

SDS-PAGE analysis of purified, BSA-free FTL antibody (clone FTL/1386) as confirmation of integrity and purity.