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S100A4/FSP1 belongs to the S100 super-family of proteins containing 2 EF-hand calcium-binding domains. S100 genes include at least 25 members, including S100A1-S100A18, trichohyalin, filaggrin, repetin, S100P, and S100Z. S100A4/FSP1 exerts its function via direct interaction with a number of proteins including P53, P63, non-muscle myosin IIA, 4 integrin, and liprin b1. It is overexpressed in highly metastatic cancers, which makes it useful as a marker of tumor progression.
Optimal dilution of the FSP1 antibody should be determined by the researcher.
A portion of amino acids 1-200 from the human protein was used as the immunogen for the FSP1 antibody.
Store the FSP1 antibody at 2-8oC (up to one month) or aliquot and store at -20oC (longer term).
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