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Home >> Antibodies >> Foxp3 Antibody / Scurfin

Foxp3 Antibody / Scurfin (RQ6868)

  Catalog No Formulation Size Price (USD)  
Image RQ6868 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) rat thymus, 2) mouse spleen and 3) mouse thymus tissue lysate with Foxp3 antibody. Predicted molecular weight ~47 kDa.
Availability 1-3 business days
Species Reactivity Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q99JB6
Applications Western blot : 1-2ug/ml
Limitations This Foxp3 antibody is available for research use only.
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Description

FOXP3 (forkhead box P3) is a protein involved in immune system responses. The human FOXP3 genes contain 11 coding exons. Exon-intron boundaries are identical across the coding regions of the mouse and human genes. By genomic sequence analysis, the FOXP3 gene maps to the p arm of the X chromosome(specifically, Xp11.23). A member of the FOX protein family, FOXP3 appears to function as a master regulator in the development and function of regulatory T cells. While the precise control mechanism has not yet been established, FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription.

Application Notes

Optimal dilution of the Foxp3 antibody should be determined by the researcher.

Immunogen

Amino acids EPEEFLKHCQADHLLDEK from the mouse protein were used as the immunogen for the Foxp3 antibody.

Storage

After reconstitution, the Foxp3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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