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Home >> Antibodies >> FOXP3 Antibody

FOXP3 Antibody (R30134)

  Catalog No Formulation Size Price (USD)  
Image R30134 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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IHC-P: FOXP3 antibody testing of human tonsil tissue
IHC-P: FOXP3 antibody testing of mouse spleen tissue
IHC-P: FOXP3 antibody testing of rat spleen tissue
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Gene ID 50943
Localization Nuclear
Applications IHC (FFPE) : 0.5-1ug/ml
Limitations This FOXP3 antibody is available for research use only.
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Description

Forkhead box P3 is a protein involved in immune system responses. The human FOXP3 genes contain 11 coding exons. Exon-intron boundaries are identical across the coding regions of the mouse and human genes. By genomic sequence analysis, the gene maps to the p arm of the X chromosome(specifically, Xp11.23). A member of the FOX protein family, FOXP3 appears to function as a master regulator in the development and function of regulatory T cells. While the precise control mechanism has not yet been established, FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription.

Application Notes

The stated application concentrations are suggested starting points. Titration of the FOXP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

Human partial recombinant protein (AA 101-431) was used as the immunogen for this FOXP3 antibody.

Storage

After reconstitution, the FOXP3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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