- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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FOXP1 Antibody / Forkhead Transcription Factor Antibody recognizes FOXP1, a member of the forkhead box P subfamily of transcription factors that regulate gene expression during development, cellular differentiation and tissue homeostasis. FOXP1 functions primarily as a transcriptional regulator by binding specific DNA sequences and interacting with co-regulatory proteins to activate or repress target genes depending on cellular context. It is widely expressed in lymphoid tissues, heart, lung, brain and numerous epithelial cell types, reflecting its diverse biological roles. NSJ Bioreagents offers FOXP1 antibodies to support studies of developmental biology, immunology and cancer research.
FOXP1 is essential for normal B cell maturation, T cell differentiation and maintenance of immune homeostasis. During development, it contributes to organogenesis of the heart, lung and central nervous system while helping regulate cellular proliferation and lineage commitment. Within the nervous system, FOXP1 participates in neuronal differentiation, cortical development and the establishment of neural circuits involved in cognition and motor function. A FOXP1 Antibody is therefore valuable for investigating transcriptional programs that coordinate tissue development and specialized cell identity.
Dysregulated FOXP1 expression has been associated with numerous malignancies, including diffuse large B-cell lymphoma, mucosa-associated lymphoid tissue lymphoma, chronic lymphocytic leukemia and several solid tumors. Depending on tissue context, FOXP1 may function as either a tumor suppressor or an oncogenic transcriptional regulator by influencing cell survival, proliferation and differentiation pathways. Altered FOXP1 activity has also been linked to neurodevelopmental disorders, congenital heart disease and immune dysfunction, making it an important biomarker across multiple areas of biomedical research. Researchers frequently use FOXP1 Antibody to examine nuclear expression patterns, characterize lymphoid malignancies and investigate transcriptional regulation in normal and diseased tissues.
An FOXP1 Antibody is a valuable reagent for detecting this forkhead transcription factor by Western blotting, immunohistochemistry, immunofluorescence, flow cytometry and related immunoassays. A Forkhead Transcription Factor Antibody supports investigations of transcriptional regulation, immune cell development, neurobiology, organogenesis and cancer biology.
Researchers studying gene regulation and DNA-binding proteins may also be interested in our Transcription Factor Antibodies page, featuring antibodies against transcriptional regulators involved in development, immunity, differentiation and cancer biology.
Optimal dilution of the FOXP1 Antibody / Forkhead Transcription Factor Antibody should be determined by the researcher.
Amino acids DFDHDRDYEDEPVNEDME from the human protein were used as the immunogen for the FOXP1 antibody.
After reconstitution, the FOXP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
FOXP1 antibody, Forkhead Transcription Factor antibody, Forkhead Box Protein P1 antibody, HSPC215 antibody
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