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Home >> Antibodies >> FOXP1 Antibody / Forkhead Transcription Factor Antibody

FOXP1 Antibody / Forkhead Transcription Factor Antibody (RQ5814)

  Catalog No Formulation Size Price (USD)  
Image RQ5814 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 449
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FOXP1 Antibody Human Breast Cancer IHC. Immunohistochemical staining of FFPE human breast cancer tissue using FOXP1 Antibody / Forkhead Transcription Factor Antibody. Following heat-induced epitope retrieval in pH 8.0 EDTA buffer, strong nuclear staining is observed in the malignant epithelial cells, consistent with the expected subcellular localization of the FOXP1 transcription factor. The surrounding stromal cells show comparatively lower staining intensity. This FOXP1 Antibody, a Forkhead Transcription Factor Antibody, is well suited for immunohistochemical studies of transcriptional regulation, breast cancer biology and FOXP1 expression in tumor tissues.
FOXP1 Antibody Human Rectal Cancer IHC. Immunohistochemical staining of FFPE human rectal cancer tissue using FOXP1 Antibody / Forkhead Transcription Factor Antibody. Following heat-induced epitope retrieval in pH 8.0 EDTA buffer, strong nuclear staining is observed throughout the malignant glandular epithelial cells, consistent with the expected localization of the FOXP1 transcription factor. This FOXP1 Antibody, a Forkhead Transcription Factor Antibody, is well suited for immunohistochemical studies of transcriptional regulation, colorectal cancer biology and FOXP1 expression in tumor tissues.
FOXP1 Antibody Human Rectal Cancer IHC. Immunohistochemical staining of FFPE human rectal cancer tissue using FOXP1 Antibody / Forkhead Transcription Factor Antibody. Following heat-induced epitope retrieval in pH 8.0 EDTA buffer, prominent nuclear staining is observed in both the malignant glandular epithelial cells and a population of stromal cells within the tumor microenvironment, consistent with the nuclear localization of FOXP1. This FOXP1 Antibody, a Forkhead Transcription Factor Antibody, is well suited for immunohistochemical studies of transcriptional regulation, colorectal cancer biology and FOXP1 expression in both tumor and stromal cell populations.
FOXP1 Antibody Mouse Brain IHC. Immunohistochemical staining of FFPE mouse brain tissue using FOXP1 Antibody / Forkhead Transcription Factor Antibody. Following heat-induced epitope retrieval in pH 8.0 EDTA buffer, strong nuclear staining is observed in neuronal populations, particularly within densely populated cortical and hippocampal layers, consistent with the expected expression pattern and nuclear localization of the FOXP1 transcription factor in the central nervous system. This FOXP1 Antibody, a Forkhead Transcription Factor Antibody, is well suited for immunohistochemical studies of neuronal development, brain organization and transcriptional regulation in neural tissues.
FOXP1 Antibody Mouse Brain Tissue IHC. Immunohistochemical staining of FFPE mouse brain tissue using FOXP1 Antibody / Forkhead Transcription Factor Antibody. Following heat-induced epitope retrieval in pH 8.0 EDTA buffer, distinct nuclear staining is observed throughout numerous neuronal populations, with widespread labeling across the brain parenchyma consistent with the expected expression and nuclear localization of FOXP1. This FOXP1 Antibody, a Forkhead Transcription Factor Antibody, is well suited for immunohistochemical studies of neuronal differentiation, brain development and transcriptional regulation in the central nervous system.
FOXP1 Antibody Rat Brain IHC. Immunohistochemical staining of FFPE rat brain tissue using FOXP1 Antibody / Forkhead Transcription Factor Antibody. Following heat-induced epitope retrieval in pH 8.0 EDTA buffer, distinct nuclear staining is observed in numerous neuronal cells throughout the brain, consistent with the expected expression pattern and nuclear localization of the FOXP1 transcription factor. This FOXP1 Antibody, a Forkhead Transcription Factor Antibody, is well suited for immunohistochemical studies of neuronal differentiation, brain development and transcriptional regulation in rat neural tissues.
FOXP1 Antibody Human and Monkey WB. Western blot analysis of FOXP1 Antibody / Forkhead Transcription Factor Antibody using lysates from human MCF-7 cells (lane 1) and monkey COS-7 cells (lane 2). A specific band is detected at approximately 82 kDa in both samples, consistent with the predicted molecular weight of FOXP1. Cross-reactivity with both human and monkey lysates demonstrates recognition of this highly conserved forkhead transcription factor. This FOXP1 Antibody, a Forkhead Transcription Factor Antibody, is suitable for Western blot studies of transcriptional regulation, developmental biology, immunology and cancer research.
FOXP1 Antibody Human Mammary Cancer IHC. Immunohistochemical staining of paraffin-embedded human mammary cancer tissue using FOXP1 Antibody / Forkhead Transcription Factor Antibody. Following heat-induced epitope retrieval in pH 8.0 EDTA buffer, the tissue was stained with FOXP1 antibody at 2 ug/ml and visualized using a biotinylated secondary antibody with DAB chromogen. Distinct nuclear staining is observed in tumor cells, consistent with the transcription factor function and expected subcellular localization of FOXP1. This FOXP1 Antibody, a Forkhead Transcription Factor Antibody, is suitable for immunohistochemical studies of transcriptional regulation, breast cancer biology and tumor biomarker expression.
FOXP1 Antibody Human Breast Cancer IF. Immunofluorescent staining of paraffin-embedded human breast cancer tissue using FOXP1 Antibody / Forkhead Transcription Factor Antibody. Following heat-induced epitope retrieval in pH 8.0 EDTA buffer, the tissue was stained with FOXP1 antibody at 5 ug/ml and detected with a Fluoro550-conjugated secondary antibody (red), while nuclei were counterstained with DAPI (blue). Strong nuclear fluorescence is observed in tumor cells, consistent with the expected localization of the FOXP1 transcription factor. This FOXP1 Antibody, a Forkhead Transcription Factor Antibody, is suitable for immunofluorescence studies of transcriptional regulation, breast cancer biology and tumor biomarker expression.
FOXP1 Antibody Human Intestinal Cancer IF. Immunofluorescent staining of paraffin-embedded human intestinal cancer tissue using FOXP1 Antibody / Forkhead Transcription Factor Antibody. Following heat-induced epitope retrieval in pH 8.0 EDTA buffer, the tissue was stained with FOXP1 antibody at 5 ug/ml and detected with a Fluoro550-conjugated secondary antibody (red), while nuclei were counterstained with DAPI (blue). Strong nuclear fluorescence is observed throughout the malignant epithelial cells, consistent with the expected localization of the FOXP1 transcription factor. This FOXP1 Antibody, a Forkhead Transcription Factor Antibody, is suitable for immunofluorescence studies of transcriptional regulation, intestinal cancer biology and tumor biomarker expression.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat, Monkey
Format Antigen affinity purified
Host Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q9H334
Localization Nuclear
Applications Western Blot : 0.5-1ug/ml
Immunohistochemistry (FFPE) : 2-5ug/ml
Immunofluorescence : 5ug/ml
Limitations This FOXP1 Antibody / Forkhead Transcription Factor Antibody is available for research use only.
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Description

FOXP1 Antibody / Forkhead Transcription Factor Antibody recognizes FOXP1, a member of the forkhead box P subfamily of transcription factors that regulate gene expression during development, cellular differentiation and tissue homeostasis. FOXP1 functions primarily as a transcriptional regulator by binding specific DNA sequences and interacting with co-regulatory proteins to activate or repress target genes depending on cellular context. It is widely expressed in lymphoid tissues, heart, lung, brain and numerous epithelial cell types, reflecting its diverse biological roles. NSJ Bioreagents offers FOXP1 antibodies to support studies of developmental biology, immunology and cancer research.

FOXP1 is essential for normal B cell maturation, T cell differentiation and maintenance of immune homeostasis. During development, it contributes to organogenesis of the heart, lung and central nervous system while helping regulate cellular proliferation and lineage commitment. Within the nervous system, FOXP1 participates in neuronal differentiation, cortical development and the establishment of neural circuits involved in cognition and motor function. A FOXP1 Antibody is therefore valuable for investigating transcriptional programs that coordinate tissue development and specialized cell identity.

Dysregulated FOXP1 expression has been associated with numerous malignancies, including diffuse large B-cell lymphoma, mucosa-associated lymphoid tissue lymphoma, chronic lymphocytic leukemia and several solid tumors. Depending on tissue context, FOXP1 may function as either a tumor suppressor or an oncogenic transcriptional regulator by influencing cell survival, proliferation and differentiation pathways. Altered FOXP1 activity has also been linked to neurodevelopmental disorders, congenital heart disease and immune dysfunction, making it an important biomarker across multiple areas of biomedical research. Researchers frequently use FOXP1 Antibody to examine nuclear expression patterns, characterize lymphoid malignancies and investigate transcriptional regulation in normal and diseased tissues.

An FOXP1 Antibody is a valuable reagent for detecting this forkhead transcription factor by Western blotting, immunohistochemistry, immunofluorescence, flow cytometry and related immunoassays. A Forkhead Transcription Factor Antibody supports investigations of transcriptional regulation, immune cell development, neurobiology, organogenesis and cancer biology.

Researchers studying gene regulation and DNA-binding proteins may also be interested in our Transcription Factor Antibodies page, featuring antibodies against transcriptional regulators involved in development, immunity, differentiation and cancer biology.

Application Notes

Optimal dilution of the FOXP1 Antibody / Forkhead Transcription Factor Antibody should be determined by the researcher.

Immunogen

Amino acids DFDHDRDYEDEPVNEDME from the human protein were used as the immunogen for the FOXP1 antibody.

Storage

After reconstitution, the FOXP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Alternate Names

FOXP1 antibody, Forkhead Transcription Factor antibody, Forkhead Box Protein P1 antibody, HSPC215 antibody

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