- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Related Products
|
FOXP1 Antibody / Forkhead Box Protein P1 Antibody recognizes Forkhead Box Protein P1 (FOXP1), a DNA-binding transcription factor belonging to the forkhead box P subfamily. FOXP1 regulates gene expression programs that control cellular differentiation, proliferation and tissue development through sequence-specific DNA binding and interactions with transcriptional co-regulators. It is broadly expressed in lymphoid tissues, heart, lung, brain and epithelial organs, reflecting its essential roles in normal physiology. NSJ Bioreagents offers FOXP1 antibodies to support investigations of developmental biology, immunology, neuroscience and oncology.
Forkhead Box Protein P1 is a key regulator of immune cell development, particularly within B lymphocytes and T lymphocytes, where it influences lineage specification, maturation and functional responses. During embryonic development, FOXP1 contributes to formation of the cardiovascular system, lungs and central nervous system while helping coordinate cellular differentiation and organogenesis. In the brain, FOXP1 is highly expressed in selected neuronal populations and participates in neural circuit formation, synaptic maturation and higher cognitive function. A FOXP1 Antibody is therefore valuable for studying transcriptional networks that govern normal development and tissue-specific gene expression.
Altered expression or mutation of FOXP1 has been implicated in diffuse large B-cell lymphoma, mucosa-associated lymphoid tissue lymphoma, chronic lymphocytic leukemia and numerous solid tumors. Depending on cellular context, Forkhead Box Protein P1 may function as either a tumor suppressor or an oncogenic transcriptional regulator. Germline variants in FOXP1 are also associated with neurodevelopmental disorders characterized by intellectual disability, language impairment and autism spectrum features. Researchers frequently use FOXP1 Antibody to examine nuclear protein expression, investigate transcriptional regulation and characterize disease-associated changes in FOXP1 signaling.
An FOXP1 Antibody is a valuable reagent for detecting Forkhead Box Protein P1 by Western blotting, immunohistochemistry, immunofluorescence, flow cytometry and related immunoassays. A Forkhead Box Protein P1 Antibody supports studies of transcriptional regulation, immune cell biology, neuronal development, organogenesis and cancer research.
For an overview of FOXP1 biology and its roles in transcriptional regulation, development and cancer, visit our FOXP1 Antibody / Forkhead Transcription Factor Antibody page.
Optimal dilution of the FOXP1 Antibody / Forkhead Box Protein P1 Antibody should be determined by the researcher.
A recombinant fragment (within amino acids 350-450) of human FOXP1 protein was used as the immunogen for the FOXP1 antibody.
Aliquot the FOXP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
FOXP1 antibody, Forkhead Box Protein P1 antibody, HSPC215 antibody, QRF1 antibody
Your bulk quote request has been submitted successfully!
Please contact us if you have any questions.