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Home >> Antibodies >> FOXC1 Antibody

FOXC1 Antibody (RQ5578)

  Catalog No Formulation Size Price (USD)  
Image RQ5578 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 439
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Western blot testing of human HEK293 cell lysate with FOXC1 antibody. Predicted molecular weight: ~57 kDa, routinely observed at up to 75 kDa.
Western blot testing of human 293T cell lysate with FOXC1 antibody. Predicted molecular weight: ~57 kDa, routinely observed at up to 75 kDa.
Immunofluorescent staining of FFPE human HeLa cells with FOXC1 antibody (green) and Alpha Tubulin mAb (red). HIER: steam section in pH6 citrate buffer for 20 min.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q12948
Applications Western Blot : 0.5-1ug/ml
Immunofluorescence : 5ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This FOXC1 antibody is available for research use only.
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Description

Forkhead box C1, also known as FOXC1, is a protein which in humans is encoded by the FOXC1 gene. It is mapped to 6p25.3. This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly.

Application Notes

Optimal dilution of the FOXC1 antibody should be determined by the researcher.

Immunogen

A human recombinant protein (amino acids T392-F554) was used as the immunogen for the FOXC1 antibody.

Storage

After reconstitution, the FOXC1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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