- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
FOXC1 Antibody (R35797)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
R35797-100UG | 0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide | 100 ug | 475 |
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse, Zebrafish |
| Format | Antigen affinity purified |
| Host | Goat |
| Clonality | Polyclonal (goat origin) |
| Isotype | Goat Ig |
| Purity | Antigen affinity |
| Gene ID | 2296 |
| Applications | Western Blot : 1-3ug/ml Immunohistochemistry (FFPE) : 4-6ug/ml ChIP : suitable ELISA (peptide) LOD : 1:4000 |
| Limitations | This FOXC1 antibody is available for research use only. |
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FOXC1 Antibody detects FOXC1, a transcription factor belonging to the FOX family of regulatory proteins that control cellular identity, developmental patterning, and gene expression. FOXC1 serves as a master regulator of transcriptional programs required for normal tissue formation and structural organization throughout vertebrate development. Through its ability to coordinate expression of genes involved in differentiation and morphogenesis, FOXC1 influences the formation of diverse tissues and contributes to maintenance of cellular function in both embryonic and adult systems. FOXC1 Antibody is frequently used to study developmental regulation and transcription factor biology.
As a nuclear protein, FOXC1 regulates transcription by binding specific DNA sequences within promoters and enhancer elements of target genes. This activity enables FOXC1 to integrate developmental signals and direct cellular responses that shape tissue architecture and developmental outcomes. The protein participates in gene regulatory networks that govern mesenchymal development, neural crest-derived structures, vascular biology, and tissue organization.
FOXC1 remains biologically relevant beyond embryogenesis, where it contributes to tissue maintenance, cellular adaptation, and regulation of differentiation-associated pathways. Researchers frequently investigate FOXC1 expression to better understand how transcription factors coordinate long-term control of cellular phenotype and tissue-specific gene expression programs. These functions have established FOXC1 as an important marker in studies of developmental and regenerative biology.
Growing evidence links FOXC1 activity to cancer progression, epithelial-mesenchymal transition, cellular migration, and therapeutic response. Changes in FOXC1 expression can alter transcriptional networks that influence tumor behavior and cellular plasticity, making the protein an important target in oncology research. Its involvement in both developmental and disease-related pathways has expanded interest in FOXC1 across multiple research disciplines.
FOXC1 Antibody is useful for investigations of transcriptional regulation, developmental biology, stem cell signaling, tissue morphogenesis, cancer biology, cellular differentiation, and gene regulatory networks. Validation may include immunohistochemistry, western blotting, immunofluorescence, flow cytometry, and additional protein detection applications when supported by experimental data.
Learn more about FOXC1 expression, developmental transcriptional regulation, tissue patterning, and stem cell-associated signaling on our FOXC1 Antibody / Forkhead Transcription Factor Antibody page.
Optimal dilution of the FOXC1 antibody should be determined by the researcher.
Amino acids RTSGAFVYDCSKF were used as the immunogen for this FOXC1 antibody.
Aliquot and store the FOXC1 antibody at -20oC.
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