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Home >> Antibodies >> FosB Antibody

FosB Antibody (R30550)

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  Catalog No Formulation Size Price (USD)  
Image R30550 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of FosB antibody and Lane 1: HT1080; 2: SW620; 3: HeLa; 4: SMMC-7721; 5: MM453 cell lysate. Expected/observed molecular weight ~36 kDa.
Western blot testing of FosB antibody and Lane 1: HT1080; 2: SW620; 3: HeLa; 4: SMMC-7721; 5: MM453 cell lysate. Expected/observed molecular weight ~36 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt P53539
Localization Nuclear
Applications Western blot : 0.5-1ug/ml
Limitations This FosB antibody is available for research use only.
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Description

FBJ murine osteosarcoma viral oncogene homolog B is a protein that in humans is encoded by the FOSB gene. It is a member of Fos gene family which consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. The proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Delta FOSB is a truncated splice variant of FOSB. It has been implicated in the development of drug addiction and control of the reward system in the brain, and is linked to changes in a number of other gene products such as CREB and sirtuins. It also regulates the commitment of mesenchymal precursor cells to the adipocyte or osteoblast lineage.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the FosB antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

An amino acid sequence from the N-terminus of human FosB (MFQAFPGDYDSGSRC) was used as the immunogen for this FosB antibody (100% homologous in human, mouse and rat).

Storage

After reconstitution, the FosB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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