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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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Folate hydrolase 1 (FOLH1), also known as Prostate-specific membrane antigen (PSMA), has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression. [UniProt]
Researchers studying prostate cancer biology, PSMA-associated signaling, and folate metabolism pathways may also be interested in our FOLH1 Antibody / Prostate Cancer and PSMA Marker page featuring validated immunohistochemistry, western blot, and protein microarray specificity data for prostate cancer research.
The stated application concentrations are suggested starting points. Titration of the FOLH1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 232-433 from the human protein was used as the immunogen for this FOLH1 antibody.
Store the FOLH1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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