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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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Flotillin 1 Antibody / Lipid Raft Marker Antibody detects FLOT1, a membrane-associated scaffolding protein involved in lipid raft organization, membrane microdomain formation, vesicle trafficking and cell signaling regulation. Flotillin 1, also known as Reggie 2, is a member of the highly conserved flotillin protein family and contains an SPFH domain that supports membrane association and protein-protein interactions. Flotillin proteins are enriched in cholesterol-rich lipid raft regions of the plasma membrane, where they help organize signaling complexes and regulate communication between the cell surface and intracellular pathways. Because of its role in membrane architecture, Flotillin 1 is widely studied as a marker of lipid rafts and membrane-associated signaling platforms.
Flotillin 1 contributes to multiple cellular processes including endocytosis, receptor trafficking, cytoskeletal organization and signal transduction. Unlike classical caveolin-dependent structures, flotillin-associated membrane domains represent distinct microdomains involved in organizing receptors and regulatory proteins at the cell membrane. FLOT1 has been linked to pathways controlling cellular adhesion, migration and responses to extracellular signals. Flotillin 1 Antibody is commonly used to study membrane organization, lipid raft biology and the regulation of proteins involved in cellular communication and intracellular transport.
Research involving Flotillin 1 has expanded into areas including cancer biology, neuroscience, immune signaling and extracellular vesicle studies. Altered FLOT1 expression has been investigated in multiple tumor types due to its association with signaling pathway regulation, proliferation, invasion and metastasis-related processes. Flotillin 1 is also studied as a component of exosomes and other membrane-derived vesicles, providing insight into mechanisms of intercellular communication. Its connection to membrane trafficking and signaling makes Flotillin 1 Antibody an important tool for researchers investigating how changes in membrane organization influence cellular behavior.
Flotillin 1 Antibody applications include analysis of FLOT1 expression, localization and regulation in biological samples using techniques such as Western blot, immunohistochemistry, immunofluorescence and flow cytometry. Detection of Flotillin 1 supports studies of lipid raft structure, membrane microdomains, vesicle transport and signaling networks that regulate normal and disease-associated cellular functions. NSJ Bioreagents provides Flotillin 1 Antibody / Lipid Raft Marker Antibody for researchers studying membrane biology, intracellular trafficking and cell signaling pathways.
Flotillin 1 Antibody detects a lipid raft-associated membrane scaffold protein involved in membrane organization, endocytosis and vesicle trafficking, making it a useful marker for research areas featured in our Cell Biology Antibodies page.
The stated application concentrations are suggested starting amounts. Titration of the Flotillin 1 Antibody / Lipid Raft Marker Antibody may be required due to differences in protocols and secondary/substrate sensitivity.
An amino acid sequence from the middle region of human FLOT1 (KKAAYDIEVNTRRAQA) was used as the immunogen for this Flotillin 1 antibody.
After reconstitution, the Flotillin 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
FLOT1 Antibody, Reggie 2 Antibody, Flotillin-1 Antibody, Flotillin 1 Lipid Raft Protein Antibody, Membrane Microdomain Protein Antibody, Caveolae Associated Protein Antibody
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